Assembly pathways of the actin cytoskeleton

Actin filaments play a critical role as part of the cytoskeleton, where they are involved in most cellular processes including determination of cell shape, cell migration, cell division, membrane function and intracellular transport.  This enormous functional specialisation is associated with differences in filament organisation, dynamics and interaction with actin-binding proteins. We aim to elucidate the fundamental molecular mechanisms that drive the self-assembly of functionally distinct actin filaments.

Scientia PhD scholarship available: http://www.2025.unsw.edu.au/apply/scientia-phd-scholarships/mathematical-biophysics-single-molecule-fluorescence-and-protein-protein