Maté Biro

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How do T cells search and destroy cancer cells?

Maté wants to know how immune cells track down and kill cancer cells—specifically how the T cell’s cytoskeleton drives the scanning for and interactions with tumour cells once they are found.

With intravital and high-speed imaging, Maté and his team watch how T cells and their cancerous targets migrate through the body—or a 3D matrix.

Using single molecule microscopes available at Single Molecule Science at UNSW, they will now be able to see and quantitate the intricate dynamics and interactions of actin—a major component of the cytoskeleton—in driving immune and cancer cell movements.

Link to EMBL Australia, NSW Node – Biro Group